Empowering you Organically – Season 2 – Episode 13
Title: What’s Nature’s Most Versatile Healing Plant?
Hosts: Jonathan Hunsaker & TeriAnn Trevenen
Guest: John Malanca
Description: In this episode, we talk with John Malanca about cannabis! We tackle topics like, what is cannabis, how it used medically, the difference between THC and CBD, and much more!
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Fact: Most cancer patients do not die from cancer, but malnutrition.
John’s Introduction into Medical Cannabis
- In 2011, father-in-law was battling stage 4 lung cancer, couldn’t eat, and was on oxygen 24/7.
- The doctor gave him two weeks to live.
- Started using a coconut oil capsule infused with raw and heated cannabis.
- Within 24 hours he was eating, by day 8 he was walking around the house.
- At the 3 month mark, switched to a full extract cannabis oil – administering a minute amount in the evening.
- Within 6 months he was walking, driving, and Hospice fired him as a patient!
- By the 9th month, he had the first scan to show, “No evidence of recurrent disease.”
- After 17 lung and brain scans showing no evidence of recurrent disease! He is still healthy and happy today – 8 years later!
United Patients Group
- Founded by John and Corrine Malanca to fill the information void surrounding medical cannabis.
- Don’t sell products – strictly education and information.
- Teach local, state, international governments, as well as local, state and international medical institutions about medical cannabis.
- All courses are CME approved continuing medical education.
What is cannabis?
Cannabis (/ˈkænəbɪs/) is a genus of flowering plants in the family Cannabaceae.
- Also known as Hemp if less than .03% THC in the composition of the plant
Three species may be recognized:
- Cannabis Sativa – formulations that include more uplifting, “day time” feelings
- Cannabis Indica – formulations that include more sedative and relaxing effects, including pain reduction
- Cannabis Ruderalis – (not discussed in the interview) naturally low concentrations of THC occurring, more research is being done on this variation of the species
- Cannabis Hybrid – formulations that are mixes of Sativa and Indica based plants made from crossbreeding
- There are currently 483 known compounds in the plant.
- The main psychoactive part of cannabis is tetrahydrocannabinol (THC). Although this is the main psychoactive components of the plant, it is also one of the main cannabinoids needed and used in medical treatments when Cannabis is on the protocol.
- Contains at least 113 cannabinoids
Two Known Subtypes of Cannabinoid Receptors
First discovered in the 1980s. Located throughout the body. Part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory, and more that have since been researched. These receptors are all over our body, head to toe.
- The CB1 receptor is expressed mainly in the brain (central nervous system or “CNS”), but also in the lungs, liver and kidneys.
- These receptors are thought to be one of the most widely expressed Gαi protein-coupled receptors in the brain
- The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells.
- These receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells.
- They also have a function in keratinocytes.
- They are also expressed on peripheral nerve terminals. These receptors play a role in antinociception, or the relief of pain.
What are Cannabinoids?
A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain.
- 113 cannabinoids have been isolated from the Cannabis plant.
- Research shows the effect of cannabinoids might be modulated by aromatic compounds produced by the cannabis plant, called terpenes as well as by the other cannabinoids.
- This interaction would lead to the entourage effect.
Medical Uses
Medical cannabis (or medical marijuana) refers to the use of cannabis and its constituent cannabinoids, as well as terpenes, to treat disease or improve symptoms relief.
- reduce nausea and vomiting during chemotherapy
- improve appetite in people with HIV/AIDS or cancer
- treat chronic pain and muscle spasms (MS and other nerve related pain)
- lessens tremors in Parkinson’s Disease
- control seizures
- reduce pain of cluster headaches in minutes
- cannabinoids are under preliminary research for their potential to affect stroke
- THC has been shown to kill cancer cells
- CBD has been shown to stop cancer cells and prevent the spread
- Many more!
Delivery Systems – Ways to Consume Medical Cannabis
- Sublingual absorption
- Topical
- Vaporization
- Suppositories
- Transdermal patches
- Edibles
Deeper Dive Resources
John Malanca:
https://www.linkedin.com/in/john-malanca-7807956b
https://unitedpatientsgroup.com/about-cancer-and-medical-cannabis/
United Patients Group:
https://unitedpatientsgroup.com/
https://www.facebook.com/UnitedPatientsGroup/
The Sacred Plant:
http://thesacredplant.online/t?orid=614242&opid=796&sid=D18L1_podcast
https://www.facebook.com/oursacredplant/
Cannabis:
https://en.wikipedia.org/wiki/Cannabis
Indica vs Sativa:
https://www.leafly.com/news/cannabis-101/sativa-indica-and-hybrid-differences-between-cannabis-types
Ruderalis:
https://www.leafly.com/news/cannabis-101/what-is-cannabis-ruderalis
Cannabinoids:
https://en.wikipedia.org/wiki/Cannabinoid
Entourage Effect:
https://en.wikipedia.org/wiki/Entourage_effect
Side by Side Image of Cannabis and Lyrica:
https://unitedpatientsgroup.com/blog/2014/06/30/fibromyalgia-big-pharma-vs-medical-cannabis
Laws By State:
https://unitedpatientsgroup.com/Medical-Marijuana-Laws-By-State
Studies in 2018:
- Cannabis Is Safe and Effective at Treating Pain in the Elderly
- CBD Protects Against the Damaging Effects of Iron in Aging Brain Diseases
- A Case for Balanced THC and CBD in Colorectal Cancer Prevention
- CBD Protects Against Endometrial Cancer by Activating TRPV1 Receptors
- THC Enhances the Pain-Relieving Effects of Opioids in Double-Blinded, Placebo-Controlled Study
- THC Boosts the Efficacy of a Traditional Neuropathic Pain Medication
- CBD Blocks Toxin’s Ability to Promote Schizophrenia-like Symptoms
- Cannabis Protects Against Alcohol’s Damaging Effects on the Stomach
- A Balanced Cannabis Approach May Treat Spasticity in ALS
- Cannabis Smoke Improves Working Memory in Underperformers
- The Entourage Effect in Rodent-Model Breast Cancer
- A Deeper Understanding of Cannabis’s Anti-Nausea Effects
- A Shift in Cannabis & Schizophrenia Theory
- Clinical Trial Finds Benefits of CBD in Autism
- A Novel Target for Low-Dose CBD Is Identified
- CBD Treats Brain Changes Caused by Regular Cannabis Use
- Transdermal CBD for the Treatment of Non-Opioid Addictions
- Plant-Derived Cannabinoids Improve the Efficacy of Cancer Treatment
- CBD’s Fast-Acting, Long-Lasting Antidepressant Effects in Rodents
- Cannabis-Based Pharmaceutical Improves Symptoms of Multiple Sclerosis